Common chemical used in plastics can feminise males & masculinise females, study finds
The world of plastics has been a topic of concern in recent years, with the harmful effects of plastic pollution and the chemicals used in their production coming under scrutiny. One such chemical, Bisphenol A (BPA), has been found to have a profound impact on the development of males and females, even at very low doses. A recent study published in the journal Communications Medicine has revealed that exposure to BPA before birth can cause sex-specific changes in metabolism and the immune system.
The study, which was conducted on mice, found that even small amounts of BPA can alter the expression of genes involved in metabolism and immune function. The effects were found to be sex-specific, with females becoming more masculine and males becoming more feminine. This is a significant finding, as it suggests that exposure to BPA can have a profound impact on the development of an individual’s sex characteristics.
The study’s first author noted that “Even very low doses changed how the genes were expressed. Females were masculinised and males were feminised.” This is a concerning finding, as it suggests that BPA can have a significant impact on the development of an individual’s sex characteristics, even at very low doses. The study’s findings have significant implications for our understanding of the impact of BPA on human health, particularly in the context of fetal development.
BPA is a chemical compound that is commonly used to make plastics and is also used in food packaging. It is known to be an endocrine disruptor, meaning that it can interfere with the body’s hormonal system. The effects of BPA on human health have been the subject of much debate, with some studies suggesting that it can cause a range of health problems, including cancer, reproductive issues, and neurological problems.
The study’s findings are particularly concerning, as they suggest that BPA can have a significant impact on the development of an individual’s sex characteristics. The study found that females exposed to BPA before birth had increased levels of testosterone, a hormone typically associated with males. Similarly, males exposed to BPA had decreased levels of testosterone and increased levels of estrogen, a hormone typically associated with females.
The study’s findings have significant implications for our understanding of the impact of BPA on human health. The fact that even very low doses of BPA can cause sex-specific changes in metabolism and the immune system suggests that the chemical can have a profound impact on the development of an individual’s sex characteristics. This is a concerning finding, as it suggests that exposure to BPA can have a significant impact on the health and wellbeing of individuals, particularly in the context of fetal development.
The study’s authors note that the findings have significant implications for the regulation of BPA. The chemical is currently used in a wide range of products, including food packaging, water bottles, and dental materials. The study’s findings suggest that the use of BPA in these products should be reassessed, particularly in the context of fetal development.
In conclusion, the study’s findings are a significant concern, as they suggest that BPA can have a profound impact on the development of an individual’s sex characteristics. The fact that even very low doses of BPA can cause sex-specific changes in metabolism and the immune system suggests that the chemical can have a significant impact on the health and wellbeing of individuals, particularly in the context of fetal development. As such, it is essential that the use of BPA in products is reassessed, and that individuals take steps to minimize their exposure to the chemical.
The study’s findings are a timely reminder of the need for greater awareness of the impact of chemicals on human health. As we continue to learn more about the effects of BPA and other chemicals on our health, it is essential that we take steps to minimize our exposure to these substances. This can involve making informed choices about the products we use, avoiding products that contain BPA, and supporting policies that regulate the use of the chemical.
In the meantime, the study’s findings serve as a significant warning about the potential health risks associated with BPA. As we continue to learn more about the effects of the chemical on human health, it is essential that we take steps to protect ourselves and our loved ones from the potential harm caused by BPA.
News source: https://www.uu.se/en/news/2025/2025-10-27-bisphenol-a-causes-sex-specific-changes-in-metabolism-and-the-immune-system