Common chemical used in plastics can feminise males & masculinise females, study finds
The world of plastics and food packaging has been under scrutiny for years due to the potential health risks associated with certain chemicals used in their production. One such chemical, Bisphenol A (BPA), has been a subject of concern among researchers and health experts. A recent study published in the journal Communications Medicine has shed new light on the effects of BPA on the human body, particularly in relation to sex-specific changes in metabolism and the immune system.
The study, conducted by a team of researchers, found that exposure to small amounts of BPA before birth can have significant effects on the development of males and females. The researchers discovered that even very low doses of BPA can alter the expression of genes, leading to feminization of males and masculinization of females. This finding has significant implications for our understanding of the impact of BPA on human health and development.
BPA is a chemical compound commonly used in the production of plastics and epoxy resins. It is widely used in food packaging, water bottles, and other consumer products. The chemical has been shown to leach into food and water, particularly when heated, and has been detected in the bodies of nearly all humans. While the effects of BPA on human health have been a subject of debate, the new study provides evidence that exposure to BPA can have sex-specific effects on metabolism and the immune system.
The study’s first author noted that “even very low doses changed how the genes were expressed. Females were masculinised and males were feminised.” This finding suggests that BPA exposure can disrupt the normal development of sex-specific traits, leading to changes in metabolism and immune function. The researchers used a mouse model to study the effects of BPA exposure on fetal development and found that the chemical altered the expression of genes involved in metabolism and immune function.
The study’s findings have significant implications for human health, particularly in relation to the development of diseases such as obesity, diabetes, and autoimmune disorders. The researchers suggest that exposure to BPA during critical periods of development, such as fetal development, may contribute to the development of these diseases. Furthermore, the study highlights the need for further research into the effects of BPA on human health and the importance of reducing exposure to this chemical.
The effects of BPA on human health are not limited to fetal development. Exposure to BPA has been linked to a range of health problems, including reproductive issues, cancer, and neurological disorders. The chemical has been shown to mimic the effects of estrogen in the body, leading to changes in hormone regulation and development. The new study adds to the growing body of evidence that BPA is a harmful chemical that should be avoided whenever possible.
So, what can be done to reduce exposure to BPA? The first step is to become aware of the products that contain BPA and to avoid them whenever possible. This includes avoiding the use of plastic water bottles, microwaving food in plastic containers, and choosing products that are labeled as BPA-free. Additionally, individuals can reduce their exposure to BPA by eating a healthy diet, avoiding packaged foods, and using glass or stainless steel containers instead of plastic.
In conclusion, the study published in Communications Medicine provides new evidence that BPA exposure can have sex-specific effects on metabolism and the immune system. The finding that even very low doses of BPA can alter the expression of genes and lead to feminization of males and masculinization of females is a significant concern for human health. As the world becomes increasingly aware of the risks associated with BPA, it is essential that we take steps to reduce our exposure to this chemical and promote a healthier environment for all.
News source: https://www.uu.se/en/news/2025/2025-10-27-bisphenol-a-causes-sex-specific-changes-in-metabolism-and-the-immune-system
About the Author
